10 Metabolic Disorders

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• drive equation left, H+ down

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Contraction

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• contracted circulating volume

Hypokalemia

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• low K in blood, K shift out of cells in exchange to H in, alkalosis

• hypokalemia leads to alkalosis

• alkalosis can also cause hypokalemia

Diuretics

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• high urine Cl when using diuretics

• low urine Cl when stopped

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• child with symptoms similar to adults taking diuretics

• increased Na delivery to CD, increased aldosterone, increased K/H secretion = hypokalemia, alkalosis

Vomiting

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• eating disorder

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• "secret"

• initial high Cl because diuretics inhibit

Hyperaldosteronism

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• no fluid overload

• urinary Cl increased due to increased Na excretion

• only time low urinary Cl is vomiting

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