12 ETC
Last updated
Last updated
takes electrons from electron carriers
2 NADH outside have to be shuttled in via malate shuttle or glycerol phosphate shuttle
mitochondria membrane convert glycerol phosphate back and generate FADH2, carry not as much energy. Some energy lost
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CoQ deliver enzymes to complex 3
iron goes back and forth in cytochrome as opposed of Hgb
oxidizes cytochrome c
phosphorylating ADP to make ATP via enzyme
ATP synthase complex 5
number of ATP generated per O2
uncoupling: ETC still working but not coupled to phosphorylation of ADP
rotenone: inhibitor of reduction of CoQ
CO binds Fe2 and competes with O2 for electron transfer
cyanide no effect on RBC with Fe2
progress to shock quickly
O2 not extracted because ETC inhibited
lactic acidosis: one of ways people die
poke a hole in inner membrane
DNP in research labs
aspirin: fever, H+ leaking out generating heat
normally lipolysis makes ATP
brown fat: not coupled ETC, lipolysis generates heat