21 Malabsorption

• vitamins, fat, sugars, proteins

• nutrient hangs around and disrupts stool formation

• no bilirubin, fat malabsorption: pale

• osmotic diarrhea: draw water out, dilute concentration

• secretory: secrete Na, water follows

Celiac

• 3 antibodies, and IgA and IgG for each

Symptoms

• gluten first goes to duodenum, thus most commonly affected

• iron absorbed in duodenum

Treatment

Complication

• T involved in pathogenesis

• each bump inflamed

Tropical

• responds to antibiotics

Whipple's

Lactose Intolerance

• no lactase

Pancreatic

Bacterial

• nerve damage from blood sugar

• diabetes with new onset diarrhea

• lactulose: sugar molecule not absorbed, laxative, osmotic agent. Bacteria metabolized to hydrogen. Measure hydrogen

Diagnosis

• nl: rise in D xylose

• nl test in lactose intolerance