14 Cerebellum

Anatomy

2 ways to see anatomy:

• anterior, posterior, flocculonodular lobes

• vermis, hermisphere

Peduncles

Inferior and middle peduncle

Superior Peduncle

• modify motor activity of cortex

• dentate most lateral located, influences same part of thalamus that basal ganglia influences

• dentate most lateral, lesions behave like lateral lesions

• other nuclei lesions behave more like medial lesions

• purkinje can modify deep nuclei

Cerebellar Lesions

• left side influences left body

Lateral lesions

• dysmetria: can't control where movement happens (touch nose/finger)

• intention tremor: begin to shake

• leg: falling because can't position

Central

• truncal: wobbly because can't hold trunk in midline

• Difficult to get feet planted in right place. If too narrow will fall over, therefore wide to avoid fall

• wide gait ataxia and falling with eyes open

• can't coordinate movement, including mouth movement

• nausea/vomiting due to area postrema triggered and increased ICP

Hereditary Ataxias

• both autosomal recessive

Ataxia Telangiectasia

• cancer usually what's fatal

Fredreich

• remember brain, heart, pancreas