11 GI Hormones

Gastrin

• secreted by stomach but travels through blood

• increase motility: gets stomach ready for digestion

• gets food going

• distended stomach from food in stomach

• ph rise from food

• abdominal pain from excessive acid

• distal duodenum, beyond normal ulcer location

• fasting important: food stimulates gastrin release

• no food, no gastrin release

• gastrin stimulate parietal cells that are destroyed

• gastrin keeps rising and rising

CCK

• delay gastric emptying to allow time for bile secretion

• triglycerides not stimulus

• taking picture of gall bladder, alternate to US

Secretin

Somatostatin

• nerves throughout body: inhibit many other things throughout body

GIP

• I for insulin. Ijk for k cell

VIP

• VIP tumors loss acid production in stomach

Motilin

• keep things moving in GI tract when not eating

Digestion