18 Hodgkin Lymphoma
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lymphocytes form mass: oma
painful: reactive lymph nodes in infection
tissue biopsy of mass/lymph node
Hodgkins
autoimmune: immune activation
Owl sitting in weeds: Hodgkin lymphoma = Reed-Sternberg cells that look like "owl's eyes"
reed sternberg only a small amt of cell in lymph nodes
most cells are reactive cells reacting to cytokines from reed sternberg: B symptoms more common
one of the reactive cells: macrophages, containing 1a hydroxylase
spread from 1 set of nodes to another, very predictable
most pt classical form
variant of reed sternberg: popcorn cells
tumor forms fibrosis tissues that surrounds tumor, creating nodules
mixed cellularity: lots of eosinophils
more the lymphocytes, better prognosis
enlargement often in nonhodgkin
most common regimen
don't memorize
