# 05 Hypoxia

## O2 Delivery

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/O2%20delivery%20to%20tissues%20components/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/MpanbtB.jpg)

![](https://f001.backblazeb2.com/file/wikiFiles/KoHfhrc.jpg)

![](https://f001.backblazeb2.com/file/wikiFiles/k8MAr7U.jpg)

* saturation of hemoglobin depends on PaO2

### PaO2

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/PaO2%20is.%20Measurement%20and%20calculation%20of%20O2%20in%20blood%20ways)..

![](https://f001.backblazeb2.com/file/wikiFiles/hM1G8od.jpg)

* in arteriole blood
* measures dissolved

![](https://f001.backblazeb2.com/file/wikiFiles/bbKH9vJ.jpg)

* measures saturation

![](https://f001.backblazeb2.com/file/wikiFiles/k8MAr7U.jpg)

* saturation of hemoglobin depends on PaO2

## Hypoxia

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/hypoxemia,%20hypoxia,%20ischemia%20differences/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/iICPQdv.jpg)

* hypoxemia: low number calculated from equation
* hypoxia can be caused by hypoxemia and other things

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/hypoxia%20causes,%20mechanisms/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/GaJ24jZ.jpg)

### HF

![](https://f001.backblazeb2.com/file/wikiFiles/4sKALyh.jpg)

* hypoxia or ischemia
* pulmonary edema with CHF: may have reduced O2 content

### Anemia

![](https://f001.backblazeb2.com/file/wikiFiles/OjRLdSr.jpg)

* O2 binding capacity reduced
* not enough Hb around

### CO

![](https://f001.backblazeb2.com/file/wikiFiles/v1mBbdh.jpg)

* functional anemia: taking Hb away from O2

![](https://f001.backblazeb2.com/file/wikiFiles/jEbeywH.jpg)

## Alveolar Gas

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/partial%20pressure%20of%20O2%20inspired,%20alveolar,%20arterial,%20symbols/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/gzZuud7.jpg)

* PAO2: O2 partial pressure in alveoli, lower because O2 exchange
* PaO2: lower because mixing of blood from vessels travel through lungs and do not go through alveoli

![](https://f001.backblazeb2.com/file/wikiFiles/eEdeBT6.jpg)

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/alveolar%20gas%20equation.%20How%20to%20find%20A-a%20gradient)..

![](https://f001.backblazeb2.com/file/wikiFiles/fIXD8HS.jpg)

* gas exchange

![](https://f001.backblazeb2.com/file/wikiFiles/czDn7lb.jpg)

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/normal%20vs%20high%20A-a%20gradient%20causes/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/3fvg433.jpg)

* high altitude: low partial pressure of O2

![](https://f001.backblazeb2.com/file/wikiFiles/DCTRJrl.jpg)


---

# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://thisispiggy.gitbook.io/my-wiki/01-step-1/pulmonary/05-hypoxia.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.