> For the complete documentation index, see [llms.txt](https://thisispiggy.gitbook.io/my-wiki/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://thisispiggy.gitbook.io/my-wiki/01-step-1/pulmonary/05-hypoxia.md).

# 05 Hypoxia

## O2 Delivery

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/O2%20delivery%20to%20tissues%20components/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/MpanbtB.jpg)

![](https://f001.backblazeb2.com/file/wikiFiles/KoHfhrc.jpg)

![](https://f001.backblazeb2.com/file/wikiFiles/k8MAr7U.jpg)

* saturation of hemoglobin depends on PaO2

### PaO2

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/PaO2%20is.%20Measurement%20and%20calculation%20of%20O2%20in%20blood%20ways)..

![](https://f001.backblazeb2.com/file/wikiFiles/hM1G8od.jpg)

* in arteriole blood
* measures dissolved

![](https://f001.backblazeb2.com/file/wikiFiles/bbKH9vJ.jpg)

* measures saturation

![](https://f001.backblazeb2.com/file/wikiFiles/k8MAr7U.jpg)

* saturation of hemoglobin depends on PaO2

## Hypoxia

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/hypoxemia,%20hypoxia,%20ischemia%20differences/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/iICPQdv.jpg)

* hypoxemia: low number calculated from equation
* hypoxia can be caused by hypoxemia and other things

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/hypoxia%20causes,%20mechanisms/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/GaJ24jZ.jpg)

### HF

![](https://f001.backblazeb2.com/file/wikiFiles/4sKALyh.jpg)

* hypoxia or ischemia
* pulmonary edema with CHF: may have reduced O2 content

### Anemia

![](https://f001.backblazeb2.com/file/wikiFiles/OjRLdSr.jpg)

* O2 binding capacity reduced
* not enough Hb around

### CO

![](https://f001.backblazeb2.com/file/wikiFiles/v1mBbdh.jpg)

* functional anemia: taking Hb away from O2

![](https://f001.backblazeb2.com/file/wikiFiles/jEbeywH.jpg)

## Alveolar Gas

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/partial%20pressure%20of%20O2%20inspired,%20alveolar,%20arterial,%20symbols/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/gzZuud7.jpg)

* PAO2: O2 partial pressure in alveoli, lower because O2 exchange
* PaO2: lower because mixing of blood from vessels travel through lungs and do not go through alveoli

![](https://f001.backblazeb2.com/file/wikiFiles/eEdeBT6.jpg)

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/alveolar%20gas%20equation.%20How%20to%20find%20A-a%20gradient)..

![](https://f001.backblazeb2.com/file/wikiFiles/fIXD8HS.jpg)

* gas exchange

![](https://f001.backblazeb2.com/file/wikiFiles/czDn7lb.jpg)

[\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Pulmonary/normal%20vs%20high%20A-a%20gradient%20causes/README.md)..

![](https://f001.backblazeb2.com/file/wikiFiles/3fvg433.jpg)

* high altitude: low partial pressure of O2

![](https://f001.backblazeb2.com/file/wikiFiles/DCTRJrl.jpg)