01 Renal Embryology

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• initiate kidney dev

• mesonephros also degenerate, except some persists as vas

• bladder not made from kidney

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• CD: only portion of nephron from ureteric bud

• metanephric duct form outgrowth, ureteric bud

• ureteric bud send signal to mesenchyme that sends signal back to ureteric bud

• interaction has to be normal for kidney dev

Pathology

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• purple: metanephric tissue

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• renal agenesis result

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• junction between ureter (7) and pelvis (6)

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[_](potter's syndrome is, result)..

• usually bilateral failure

[_](potter's syndrome causes)..

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• can't rise in abdomen

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• key feature: cancer at dome