02 Gene Mapping
Last updated
Last updated
The law of segregation describes the phenomenon in which gametogenesis results in the separation of paired chromosomes so that the offspring inherit only half of each parent's genetic composition.
50% chance gametes will have parental version of genes
50% chance of either having FM or fm
50% chance for recombinant
use frequency of recombination of genes to determine how far each gene is away from each other
recombination of AB 16%
AB farther apart, higher frequency of recombination
AC closer, smaller frequency
even with large family, may never see recombination event
expected frequency of mixture of allele
if expected similar to reality = linkage equilibrium
not similar to Hardy Weinberg law (same gene, different alleles)
closer together = greater linkage disequilibrium
use linkage disequilibrium to study genes close together that can't study with family
at first, disequilibrium highest because closest together
with later generations, farther apart, more in equilibrium
