09 Gm Indeterminate

Coxiella Burnetii

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• Originally rickettsia species, now its own

• red barn: Gram negative

• Ram inside barn with lock: Obligate intracellular organism

• Walnuts with poop: Contained in spore like structures in animal feces

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• Walnuts with poop: Contained in spore like structures in animal feces

• Dust cloud: Transmitted to humans via aerosol transmission, farm animals are major reservoir

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• White, clean sheep: No rash caused

• Q horn; Q-fever

• coughing farmer: Pneumonia

• hitting head: Headache

• sweating/red face: Fever

• Liver spot: May cause hepatitis

• Self limiting

Mycoplasma Pneumoniae

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• Outside, no walls: "No cell wall, can't appear on gram stain"

• cholesterol rings on goal net: Cell membrane contains cholesterol, stabilize membrane and more flexible

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• military uniform: Common in military recruits living in close quarters

• <30: Commonly occurs in young adults

[_](mycoplasma pneumoniae labs and agar. What's so special about its symptom)..

• RBC on ground bound by IgM snow flakes: IgM cold agglutinins cause agglutination/lysis of red blood cells

• Don't eat on ice: "Eaton's agar"

• patchy sky: X-ray shows reticulonodular or "patchy" infiltrate, appears much worse than patients seem clinically

• referee walking: Walking pneumonia, pt not as sick as X ray shows

• target: Erythema multiforme. Target lesions

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• Crows: Macrolide for treatment because no cell wall

Rickettsia species

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• Inside stadium: Obligate intracellular organism

• All white ppl: Poor gram staining. Giemsa stain for visualization

• pink tennis balls: Weakly gram negative

• deflated tennis balls: Coccobacillary shape

• Coach shirt: Unable to produce CoA, gets it from eukaryotic cells

• NAD+ bottle: Unable to produce NAD+, important for bacterial growth and reproduction, steal from eukaryotic

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• Will and Felix: Weil-Felix agglutination test for Rickettsial infections, cross reaction between rickettsia and proteus vulgaris

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• Felix sweating/touching head: Headache and fever in early Rickettsial infection

• Rash may be associated with vasculitis

• broken, bright red net and rackets: Vasculitis and inflammation/destruction

• Tires: Doxycycline for treatment

Prowazekii

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• Coach with military hat: Affects military camp recruits and prisoners of war (close contact with poor hygiene

• football shaped like louse: Spread by louse, defecates near bite spread to blood by scratching.

• The outbreak board: Illness is called epidemic typhus (more widespread than endemic)

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• football formation: Rash starts at trunk, and spreads outward towards extremities

• players red except helmet, hands, feet: Rash spares hands, head, and feet

• Tackled player: Causes myalgia and arthalgia

• coughing from dirt: Causes pneumonia

• confused guy: Encephalitis, with and confusion. can cause coma if very serious

rickettsii

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• Rock with legs, derma center arena: Transmitted by direct bite of Dermacentor ticks (sport center)

• Transmitted by direct bite of Dermacentor ticks

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• climber at bottom with no rash: Rash not immediate, incubation period between 2-14 days

• 1st climber: Rash begins at extremities. Wall = source of rash

• Rash spreads centrally from extremities

• Climber on top grabbing head, sweating, sore from climb: Symptoms include headache, fever, myalgias