Lupus

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• UV light may trigger

Diagnosis

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• hallmark: ANA, low C3/C4

• once antibody antigen form: circulate plasma

• on exam: ANA either positive or negative

• continue to dilute sample until can't see

• anti-dsDNA rise in flares

• ribonucleoprotein: rna and protein

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• arterial thrombosis uncommon

Symptoms

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• symptoms not constant, flares then remission

• penias: type 2 not type 3

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• serious complications are rare

Treatment

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Neonatal Lupus

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• very different

• sjogren's: very common with SSA/Ro and SSB/La (can also have these antibodies in lupus)

• not malar

• pacemaker for rest of life