04 Coagulopathies

• this lecture: coagulation cascade

• PTT normal: 30s

• platelet bleeding: superficial

Hemophillia

• A for eight

• used more often as fibrinogen restoring

Coagulation Factor Inhibitors

• looks like hemophilia A

• malignancy/autoimmune: antibodies develop

Vitamin K Deficiency

• CF patients

• neoborn: intracranial hemorrhage, increased ICP (bulging fontanelle, sunset eyes)

• both intrinsic and extrinsic pathway

• factor 7 shortest half life of all: first to fall, PT increases

Blood Transfusion

Liver Disease