19 MPGN

_..

  • some element of renal failure (increase in BUN/Cr), hematuria, proteinuria

Type 1

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  • thick knots in string: Associated with membranous glomerulonephritis

  • 3 string: Associated with membranoproliferative glomerulonephritis. Tram track appearance

  • subendothelial deposits

  • symptoms range from mild hematuria to full blown RF

Type 2

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  • electron dense deposits in basement membrane

  • complement overactivation

  • negative IF

  • symptoms range from mild hematuria to full blown RF

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