# 05 Gm Negative Respiratory Bacilli ## Bordatella pertussis [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/Bordatella%20pertussis%20transmission/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * coughing: Transmitted by respiratory droplets [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/Bordatella%20pertussis%203%20toxins/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * red bow GI: pertussis toxin * EF Shield: like anthrax * Tractor: tracheal toxin [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/pertussis%20invade%20or%20attach?%20How/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * red and blow strings: Filamentous hemagglutinin, pili used to attach to respiratory epithelium and release toxin [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/pertussis%20toxin%20MOA/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * bow and GI (military) in wheel chair: Pertussis toxin rirosylates Gi, disables Gi * army camp: Pertussis toxin increases cAMP [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/Bordatella%20pertussis%20classic%20lab%20value/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * popcorn overflowing: Lymphocytosis due to loss of chemotaxis [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/pertussis%20EF%20toxin%20MOA/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * EF shield: Adenylate cyclase toxin: acts like Anthracis EF toxin, increase cAMP [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/pertussis%20tracheal%20toxin%20part%20of,%20MOA/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * tractor cleaves grass: Tracheal toxin, peptidoglycan wall, damages ciliated cell of respiratory epithelium [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/pertussis%203%20phases%20and%20symptoms/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * Catarrhal phase: nonspecific, 1-2 weeks, conjunctival injection, lacrimation * whoop horn: Paroxysmal stage: Whooping cough * Victory banner: 100 day cough: convalescent stage can last for months, 3 months [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/pertussis%20treatment%20and%20vaccine/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/M5kyvwl.jpg) * crow: Macrolide treatment * cell phone: DTaP vaccine has acellular Pertussis antigens ## Haemophilus Influenza [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/H.%20influenza%20gm%20stain,%20shape,%20agar,%20transmission).. ![](https://f001.backblazeb2.com/file/wikiFiles/Syw2PQ6.jpg) * Phyllis: haemophilus * red color: gm negative * candy: Coccobacillary shape * chocolate on window: Grown on chocolate agar * 5 cent, nickle: factor V (nicotinamide) (NAD) added to chocolate agar (staph aureus with sheep blood) * 10 c: Factor X (hematin) added to chocolate agar * aerosol spray: Aerosol transmission * capsule with bee: encapsulated with type B * **IgA protease** [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/H.%20influenza%20symptoms%20and%20cause).. ![](https://f001.backblazeb2.com/file/wikiFiles/Syw2PQ6.jpg) * child screaming and drooling: Epiglottitis, inflammed epiglottis, inspiratory stridor, drooling * chocolate covered cherries, kid with icecream and cherry: Cherry red epiglottis * stuffed ear: Otitis media * meningitis kid: Meningitis in children * capsule with bee: Strains with type B vaccine cause meningitis [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/H.%20influenza%20vaccine,%20age).. ![](https://f001.backblazeb2.com/file/wikiFiles/Syw2PQ6.jpg) * syringe: Vaccine for H. flu type B * Dip: Vaccine is polysaccharide conjugated to Diphtheria toxoid * $2.18: Vaccine for ages 2-18 months [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/H.%20influenza%20demographics).. ![](https://f001.backblazeb2.com/file/wikiFiles/Syw2PQ6.jpg) * sickle: Increased risk of infection in sickle cell or asplenic patients [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/H.%20influenza%20treatment%20and%20prophylaxis).. ![](https://f001.backblazeb2.com/file/wikiFiles/Syw2PQ6.jpg) * 3 axes: Ceftriaxone for meningitis or systemic disease * rifle: Rifampin prophylaxis for close contacts ## Legionella pneumophila [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/legionella%20gm%20stain,%20agar,%20features/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/D5JuwmG.jpg) * red color but silver on top: Gram negative but needs silver stain to be visualized * piles of coal: Grown on charcoal yeast extract * iron anchor with cysteine: Growth requires presence of iron and cysteine * girl with ring: Oxidase positive [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/legionella%202%20diseases/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/D5JuwmG.jpg) * pontiac fever * legionnaire ### Pontiac fever [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/pontiac%20fever,%20bacteria,%20symptoms%20and%20result/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/D5JuwmG.jpg) * Legionella * Pontiac car steaming: Pontiac fever: self limited fever and malaise ### Legionnaire's disease \[\_]\(legionnaire's disease demographics, symptoms).. ![](https://f001.backblazeb2.com/file/wikiFiles/D5JuwmG.jpg) * sailor smoking: Legionnaires' disease more common in smokers * coal flame: High fever >40 or >104 * confused sailor with hurt head: May present with headache and confusion * sailor with paint all around: Pneumonia with diarrhea suggestive of Legionnaires' disease " [\_](https://github.com/thisispiggy/my-wiki/tree/601ff771dc2fac1318ae8b59435ac8485628fd81/01%20Step%201/Microbes/legionaire%20disease%20diagnosis%20and%20imaging/README.md).. ![](https://f001.backblazeb2.com/file/wikiFiles/D5JuwmG.jpg) * sailor urinating: Urine antigen test for rapid diagnosis * sailor wasting salt: Hyponatremia, <130 * map: X-ray shows patchy infiltrate with consolidation of one lobe \[\_]\(legionnaire's disease treatment).. ![](https://f001.backblazeb2.com/file/wikiFiles/D5JuwmG.jpg) * flower: Fluoroquinolone may also be used for treatment * crows: Macrolides for fever