Trinucleotide Disorders
Last updated
Last updated
polymorphic: many forms include variable number of repeats from person to person
more repeats with each generation
symptoms similar to down syndrome
brain, heart, pancreas depend on mitochondria
deacetylation
muscle disorder along with DMD, becker
loss of myotonic dystrophy protein kinase
CTG
later than other muscular dystrophies
triad: Cataracts, Toupee, Gonadal atrophy
as opposed to HF
