16 Glomerulonephritis Principles

Glomerular filtration barrier

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3 layers:

  • endothelium

  • basement membrane

  • podocytes aka epithelium

  • keep out cells

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Hematuria

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  • microscopic: normal color

  • can occur after exercise in normal kidneys

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  • clots: usually form bladder, kidney stones

  • rbc squeeze through, bunched up, form casts

Proteinuria

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  • dehydrated: concentration goes up

  • less influenced by hydration status

Glomerular Disease

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Microscopy

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