30 Gaze Palsies

Conjugate Gaze

  • look to right: begin in PPRF signal to CN 6 nucleus, innervate LR

  • MLF: CN 6 nerve fiber to contralateral CN III

  • PPRF next to MLF and CN 6 nucleus

INO

  • INO aka

  • left INO: left MLF damaged, can't gaze right

  • move left: everything ok

  • move right: midline

  • gaze right

  • LR of right eye ok

  • MLF damaged: left eye can't adduct

  • left INO

  • left INO: left eye can't gaze right

  • right INO: right eye can't gaze left

CN 6 Palsy

PPRF

  • no PPRF: can't initiate gaze to affected side

  • both eyes can't gaze right, opposed to CN 6 (only right eye can't gaze right)

One and Half

Frontal Eye Field

  • normal gaze: right and left FEF both pushing eyes equally

  • lesion: remove activation of one side, other side dominates

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