04 Neurotransmitters

CNS/PNS

• NT affects both CNS/PNS

• peripheral: sympathetic/parasympathetic

NE

• peripheral: fight/flight response

• opiate withdrawal activated sympathetic system

Dopamine

GABA

• B6 def: seizures from low GABA

• if inhibit CNS via GABA = sedation

• hyperpolarizes membrane

NA

Serotonin

Serotonin syndrome

Ach

Glutamate

• opposite GABA

PCP